Supramolecular micelle-based nucleoapzymes for the catalytic oxidation of dopamine to aminochrome

H. Bauke Albada; Jan Willem De Vries; Qing Liu; Eyal Golub; Niels Klement; Andreas Herrmann; Itamar Willner

doi:10.1039/c6cc01115b

Supramolecular micelle-based nucleoapzymes for the catalytic oxidation of dopamine to aminochrome

H. Bauke Albada, Jan Willem De Vries, Qing Liu, Eyal Golub, Niels Klement, Andreas Herrmann, Itamar Willner

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

Lipidated DNAzymes or a lipidated Cu(ii)-complex and lipidated aptamer sequences form supramolecular assemblies of micellar nucleoapzymes for the enhanced oxidation of dopamine to aminochrome. The catalytic functions of the micellar nucleoapzymes are attributed to the concentration of the substrate, using the aptamer units, in close proximity to the active sites.

Original language	English
Pages (from-to)	5561-5564
Number of pages	4
Journal	Chemical Communications
Volume	52
Issue number	32
DOIs	https://doi.org/10.1039/c6cc01115b
State	Published - 25 Apr 2016
Externally published	Yes

Bibliographical note

Funding Information:
This research was supported by the Israel Science Foundation.

Publisher Copyright:
© The Royal Society of Chemistry 2016.

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AU - Klement, Niels

AU - Herrmann, Andreas

AU - Willner, Itamar

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Supramolecular micelle-based nucleoapzymes for the catalytic oxidation of dopamine to aminochrome

Abstract

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