Superovulation and intrauterine insemination in the treatment of male factor infertility

E. Shalev, Y. Geslevich, M. Matilsky, V. Eyali, M. Ben-Ami

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Recent studies report that superovulation combined with intrauterine insemination (IUI) is more successful than superovulation alone, IUI alone or superovulation with intracervical insemination in couples with male subfertility. Our study evaluated two superovulation protocols in the management of male factor infertility using IUI: (A) clomiphene citrate and human chorionic gonadotropin (HCG) and (B) human menopausal gonadotropin and HCG. Fifteen couples with severe oligoasthenozoospermia (OAS) were treated with protocol A in 54 cycles, and no pregnancies were achieved. Eight of the 15 couples with severe OAS subsequently received protocol B for 24 cycles and elicited no pregnancies. Thirty-seven couples with moderate OAS received protocol A for 169 cycles, and 2 pregnancies ensued (5.4% per couple and 1.12% per cycle). Twelve of the 35 nonpregnant couples with moderate OAS then received protocol B for 31 cycles, and 4 pregnancies were recorded (33.3% per couple and 12.9% per cycle).

Original languageEnglish
Pages (from-to)50-53
Number of pages4
JournalGynecologic and Obstetric Investigation
Issue number1
StatePublished - 1995
Externally publishedYes


  • Intrauterine insemination
  • Male factor
  • Superovulation


Dive into the research topics of 'Superovulation and intrauterine insemination in the treatment of male factor infertility'. Together they form a unique fingerprint.

Cite this