SuFEx-based strategies for the preparation of functional particles and cation exchange resins

Andrew J. Kassick; Li Chen; Marina Kovaliov; Robert T. Mathers; Jason Locklin; Saadyah Averick

doi:10.1039/c9cc00036d

SuFEx-based strategies for the preparation of functional particles and cation exchange resins

Andrew J. Kassick, Li Chen, Marina Kovaliov, Robert T. Mathers, Jason Locklin, Saadyah Averick

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

A predictable and reproducible number of sulfuric acid sites have been achieved for cation exchange resins by employing a mild SuFEx-based reagent system to effect the hydrolysis of fluorosulfonated polymer beads. The resultant poly(hydrogen sulfate) beads effectively demonstrate their utility as cation exchange resins in ion-capture experiments. Furthermore, their polyfluorosulfonated precursors have also proven to be suitable substrates for traditional SuFEx-type click reactions in both small molecule and protein immobilization applications.

Original language	English
Pages (from-to)	3891-3894
Number of pages	4
Journal	Chemical Communications
Volume	55
Issue number	27
DOIs	https://doi.org/10.1039/c9cc00036d
State	Published - 7 Apr 2019
Externally published	Yes

Bibliographical note

Publisher Copyright:
© 2019 The Royal Society of Chemistry.

Funding

We gratefully acknowledge The Army Research Office (Award# 68271-CH) Young Investigator Program (W911NF-17-1-0015) and the Neuroscience Institute at AHN for funding.

Funders	Funder number
Neuroscience Institute
Army Research Office	W911NF-17-1-0015, 68271-CH

Access to Document

10.1039/c9cc00036d

Cite this

@article{9581e5a775fb4fed9c590692f033c710,

title = "SuFEx-based strategies for the preparation of functional particles and cation exchange resins",

abstract = "A predictable and reproducible number of sulfuric acid sites have been achieved for cation exchange resins by employing a mild SuFEx-based reagent system to effect the hydrolysis of fluorosulfonated polymer beads. The resultant poly(hydrogen sulfate) beads effectively demonstrate their utility as cation exchange resins in ion-capture experiments. Furthermore, their polyfluorosulfonated precursors have also proven to be suitable substrates for traditional SuFEx-type click reactions in both small molecule and protein immobilization applications.",

author = "Kassick, \{Andrew J.\} and Li Chen and Marina Kovaliov and Mathers, \{Robert T.\} and Jason Locklin and Saadyah Averick",

note = "Publisher Copyright: {\textcopyright} 2019 The Royal Society of Chemistry.",

year = "2019",

month = apr,

day = "7",

doi = "10.1039/c9cc00036d",

language = "אנגלית",

volume = "55",

pages = "3891--3894",

journal = "Chemical Communications",

issn = "1359-7345",

publisher = "Royal Society of Chemistry",

number = "27",

}

TY - JOUR

T1 - SuFEx-based strategies for the preparation of functional particles and cation exchange resins

AU - Kassick, Andrew J.

AU - Chen, Li

AU - Kovaliov, Marina

AU - Mathers, Robert T.

AU - Locklin, Jason

AU - Averick, Saadyah

PY - 2019/4/7

Y1 - 2019/4/7

N2 - A predictable and reproducible number of sulfuric acid sites have been achieved for cation exchange resins by employing a mild SuFEx-based reagent system to effect the hydrolysis of fluorosulfonated polymer beads. The resultant poly(hydrogen sulfate) beads effectively demonstrate their utility as cation exchange resins in ion-capture experiments. Furthermore, their polyfluorosulfonated precursors have also proven to be suitable substrates for traditional SuFEx-type click reactions in both small molecule and protein immobilization applications.

AB - A predictable and reproducible number of sulfuric acid sites have been achieved for cation exchange resins by employing a mild SuFEx-based reagent system to effect the hydrolysis of fluorosulfonated polymer beads. The resultant poly(hydrogen sulfate) beads effectively demonstrate their utility as cation exchange resins in ion-capture experiments. Furthermore, their polyfluorosulfonated precursors have also proven to be suitable substrates for traditional SuFEx-type click reactions in both small molecule and protein immobilization applications.

UR - https://www.scopus.com/pages/publications/85063963441

U2 - 10.1039/c9cc00036d

DO - 10.1039/c9cc00036d

M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???

C2 - 30843906

AN - SCOPUS:85063963441

SN - 1359-7345

VL - 55

SP - 3891

EP - 3894

JO - Chemical Communications

JF - Chemical Communications

IS - 27

ER -

SuFEx-based strategies for the preparation of functional particles and cation exchange resins

Abstract

Bibliographical note

Funding

Access to Document

Other files and links

Fingerprint

Cite this