Study of nano-mechanics of collagen I triple-helices by computerized processing of AFM images

Arkady Bitler, Emanuel Perugia, Sidney R. Cohen

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

2 Scopus citations

Abstract

We used atomic force microscope (AFM) to acquire high-resolution images of collagen type I triple-helices under ambient conditions in tapping mode. Angles between consecutive fixed-length segments were measured and analyzed to yield persistence length and elastic constant. Changing the segment length allowed exploring the mechanics at various scales. Understanding the mechanical properties of collagen molecules could serve to elucidate mechanisms of complex mechanical properties of interest in nanomedicine and nanotechnology.

Original languageEnglish
Title of host publicationFunctional Imaging of Materials-Advances in Multifrequency and Multispectral
Pages7-12
Number of pages6
DOIs
StatePublished - 2012
Externally publishedYes
Event2011 MRS Fall Meeting - Boston, MA, United States
Duration: 28 Nov 20112 Dec 2011

Publication series

NameMaterials Research Society Symposium Proceedings
Volume1422
ISSN (Print)0272-9172

Conference

Conference2011 MRS Fall Meeting
Country/TerritoryUnited States
CityBoston, MA
Period28/11/112/12/11

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