Studies on the osmotic fragility of human blood platelets

D. Nelken; N. Gilboa-Garber; J. Gurevitch

doi:10.1159/000206643

Studies on the osmotic fragility of human blood platelets

D. Nelken
, N. Gilboa-Garber
, J. Gurevitch

Hebrew University of Jerusalem

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Morphological changes of human blood platelets kept for 2 hours in various hypotonic NaCl solutions, and subsequently restored to isotonic surroundings, were studied. Cells which had changed into transitional forms with swordlike processes in NaCl concentrations of 0.40% - 0.24% could be returned to their normal morphological state. Cells which developed swordlike processes in NaCl concentrations of 0.24% or less were unable to revert to the normal state, and disintegrated into thrombocyte ghosts.

Original language	English
Pages (from-to)	75-80
Number of pages	6
Journal	Acta Haematologica
Volume	26
Issue number	2
DOIs	https://doi.org/10.1159/000206643
State	Published - 1961
Externally published	Yes

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10.1159/000206643

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title = "Studies on the osmotic fragility of human blood platelets",

abstract = "Morphological changes of human blood platelets kept for 2 hours in various hypotonic NaCl solutions, and subsequently restored to isotonic surroundings, were studied. Cells which had changed into transitional forms with swordlike processes in NaCl concentrations of 0.40\% - 0.24\% could be returned to their normal morphological state. Cells which developed swordlike processes in NaCl concentrations of 0.24\% or less were unable to revert to the normal state, and disintegrated into thrombocyte ghosts.",

author = "D. Nelken and N. Gilboa-Garber and J. Gurevitch",

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AB - Morphological changes of human blood platelets kept for 2 hours in various hypotonic NaCl solutions, and subsequently restored to isotonic surroundings, were studied. Cells which had changed into transitional forms with swordlike processes in NaCl concentrations of 0.40% - 0.24% could be returned to their normal morphological state. Cells which developed swordlike processes in NaCl concentrations of 0.24% or less were unable to revert to the normal state, and disintegrated into thrombocyte ghosts.

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Studies on the osmotic fragility of human blood platelets

Abstract

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