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Studies on A Simple Route to A Bicyclic Reserpine Intermediate

  • L. Gottlieb
  • , D. Kellner
  • , H. J.E. Loewenthal
  • Technion-Israel Institute of Technology

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

: A concise route is described to a Reserpine synthetic inter= mediate having the features of ring E and an oxygen function for constructing ring D. This involves an unusual a-diketone cleavage, the selective elaboration of the carboxylated ring in l-naphthoic acids and selective boron halide cleavage of ester and ether groups.

Original languageEnglish
Pages (from-to)2987-2997
Number of pages11
JournalSynthetic Communications
Volume19
Issue number17
DOIs
StatePublished - Nov 1989
Externally publishedYes

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