Abstract
Serotonin, a neurotransmitter and vasoconstrictor, affects various cell properties. We have analyzed the importance of its structural components for its extensive effect on human erythrocyte fragility, using its O- and N- linked derivatives and related compounds. The results presented in this communication indicate that the amino group, free of adjacent negative charges, and the hydroxyl group are indispensable for the serotonin-induced increase in red blood cell fragility.
| Original language | English |
|---|---|
| Pages (from-to) | 283-285 |
| Number of pages | 3 |
| Journal | Molecular Genetics and Metabolism |
| Volume | 64 |
| Issue number | 4 |
| DOIs | |
| State | Published - Aug 1998 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- Cell damage
- Erythrocyte fragility
- Histamine
- Monoamines
- Serotonin (5-hydroxytryptamine)
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