Structural clarification of germacranolides from Calea species

Zenaide S. Ferreira, Nídia F. Roque, Otto R. Gottlieb, Fernando Oliveira, Hugo E. Gottlieb

Research output: Contribution to journalArticlepeer-review

20 Scopus citations


The aerial parts of Calea pinnatifida contain a 4-glycosyloxybenzoic acid, anisic acid, tetradeca-4E,6E,12E-trien-8,10-diyn-1-ol and arucanolide. The structural elucidation of this germacranolide included comparison with neurolenin B whose stereochemistry had been defined by X-ray crystallographic analysis. The data suggest that the structures of all other known germacranolides of the genus Calea should be revised.

Original languageEnglish
Pages (from-to)1481-1484
Number of pages4
Issue number7
StatePublished - 1980
Externally publishedYes


  • Calea pinnatifida
  • Compositae
  • Heliantheae
  • germacranolide.
  • polyacetylene


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