Structural and Mechanistic Aspects of 3C Proteases from the Picornavirus Family

Keyphrases

• Mechanistic Aspects 100%
• 3C-like Protease (3CLpro) 100%
• Picornavirus 100%
• Virus 50%
• Viral Protease 50%
• Nucleophilic Attack 25%
• Specific Features 25%
• Rational Drug Design 25%
• Cysteine 25%
• Structural Information 25%
• Protease 25%
• Post-translational Cleavage 25%
• Disease Syndrome 25%
• Co-translational 25%
• Carbonyl Compounds 25%
• Translation Product 25%
• Oxygen nucleophiles 25%
• Rhinovirus 25%
• Sulfur nucleophiles 25%
• Serious Disease 25%
• Mechanistic Information 25%

Biochemistry, Genetics and Molecular Biology

• Protease 100%
• Picornaviridae 100%
• Enzyme 40%
• Serine 20%
• Nucleophilicity 20%
• Cysteine 20%
• Life Cycle 20%
• Rhinovirus 20%

Immunology and Microbiology

• Picornaviridae 100%
• Life Cycle 25%
• Rhinovirus 25%
• Nucleophilicity 25%