TY - JOUR
T1 - Stereoisomerism in macrocyclic bis(piperidones)
AU - Belostotskii, A. M.
AU - Shapiro, A. B.
PY - 1986/9
Y1 - 1986/9
N2 - The reaction of a polysubstituted 3,5-dimethylene-4-piperidone with aliphatic diamines leads to macrocyclic products, namely, 3,3′,5,5′-di(methylaminoalkyl-aminomethyl)-bridged bis(piperidones). The latter compounds are formed as mixtures of cis, trans-isomers, and isolated in the form of cis,cis-isomers. 13C-NMR spectral analysis has shown that these compounds also exhibit characteristic syn-anti isomerism associated with the relative orientation of the 3,5-substituents on opposite piperidone rings.
AB - The reaction of a polysubstituted 3,5-dimethylene-4-piperidone with aliphatic diamines leads to macrocyclic products, namely, 3,3′,5,5′-di(methylaminoalkyl-aminomethyl)-bridged bis(piperidones). The latter compounds are formed as mixtures of cis, trans-isomers, and isolated in the form of cis,cis-isomers. 13C-NMR spectral analysis has shown that these compounds also exhibit characteristic syn-anti isomerism associated with the relative orientation of the 3,5-substituents on opposite piperidone rings.
UR - https://www.scopus.com/pages/publications/34250101387
U2 - 10.1007/bf00478137
DO - 10.1007/bf00478137
M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???
SN - 0009-3122
VL - 22
SP - 1011
EP - 1016
JO - Chemistry of Heterocyclic Compounds
JF - Chemistry of Heterocyclic Compounds
IS - 9
ER -