TY - JOUR
T1 - Spontaneous activity recorded from the central cut end of the carotid sinus nerve of the cat [38]
AU - Biscoe, T. J.
AU - Sampson, S. R.
PY - 1967
Y1 - 1967
N2 - THE receptor in the carotid body for changes in blood gas tensions has for many years been assumed to be the glomus cell1,2 or Type I cell3. Lever, Lewis and Boyd4 showed by electron microscopy that the nerve endings adjacent to these cells contain microvesicles, of the same dimension as synaptic vesicles, and small mitochondria, and this observation was confirmed by Biscoe and Stehbens5,6, who described the structure of the endings in greater detail and showed that they are similar to those of an efferent type in other parts of the nervous system7 and share a dense junctional region with the Type I cell membrane. Biscoe and Stehbens8 later found that the endings degenerated after the carotid sinus nerve was cut, and it seemed probable, in accordance with the evidence of De Castro1,2, that they were afferent nerve endings. It is also possible, however, that such endings arise from efferent nerve fibres coursing in the carotid sinus nerve to the carotid body. The purpose of the present experiments was to seek evidence for such efferent fibres.
AB - THE receptor in the carotid body for changes in blood gas tensions has for many years been assumed to be the glomus cell1,2 or Type I cell3. Lever, Lewis and Boyd4 showed by electron microscopy that the nerve endings adjacent to these cells contain microvesicles, of the same dimension as synaptic vesicles, and small mitochondria, and this observation was confirmed by Biscoe and Stehbens5,6, who described the structure of the endings in greater detail and showed that they are similar to those of an efferent type in other parts of the nervous system7 and share a dense junctional region with the Type I cell membrane. Biscoe and Stehbens8 later found that the endings degenerated after the carotid sinus nerve was cut, and it seemed probable, in accordance with the evidence of De Castro1,2, that they were afferent nerve endings. It is also possible, however, that such endings arise from efferent nerve fibres coursing in the carotid sinus nerve to the carotid body. The purpose of the present experiments was to seek evidence for such efferent fibres.
UR - http://www.scopus.com/inward/record.url?scp=0014213389&partnerID=8YFLogxK
U2 - 10.1038/216294a0
DO - 10.1038/216294a0
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C2 - 6057953
AN - SCOPUS:0014213389
SN - 0028-0836
VL - 216
SP - 294
EP - 295
JO - Nature
JF - Nature
IS - 5112
ER -