Some pathological substrates in manual laterality

P. Satz, M. F. Green, N. Lyon

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

Anomalies in manual dominance are commonly seen in neurological and psychiatric disorders. The authors argue that some of the manual dominance anomalies in these populations spring from perturbations in the central nervous system during early development and represent trait-like biological markers. In addition, some of the anomalies represent phasic changes that are state-dependent and linked with clinical episodes. Autism and schizophrenia are used as the primary neurodevelopmental models in which to discuss these concepts of human laterality. Preliminary findings are mentioned which suggest a possible neuroanatomical correlate of atypical handedness in schizophrenia.

Original languageEnglish
Pages (from-to)25-33
Number of pages9
JournalBrain Dysfunction
Volume2
Issue number1
StatePublished - 1989
Externally publishedYes

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