Sliding of p53 along DNA can be modulated by its oligomeric state and by cross-talks between its constituent domains

Keyphrases

• Oligomeric State 100%
• Linear Diffusion 100%
• DNA Search 100%
• Salt Concentration 50%
• Cell Behavior 50%
• Protein-DNA Complex 50%
• DNA Complex 50%
• Transcription Factor 50%
• Computational Model 50%
• Electrostatic Potential 50%
• Atomic Level 50%
• P53 Protein 50%
• Cancer Development 50%
• Wiring 50%
• Missense mutation 50%
• Post-translational 50%
• N-terminus 50%
• Molecular Insight 50%
• DNA Segment 50%
• Diffusion Dynamics 50%
• P53 DNA 50%
• High Salt Concentration 50%
• Search Mechanism 50%
• Disordered Regions 50%
• Positive Regulation 50%
• Sliding Dynamics 50%
• Major Groove 50%
• Sliding Characteristics 50%
• Charge Modification 50%
• Tight Packing 50%

Biochemistry, Genetics and Molecular Biology

• P53 100%
• Facilitated Diffusion 25%
• Dynamics 25%
• N-Terminus 12%
• Static Electricity 12%
• Cell Function 12%
• Missense Mutation 12%
• Transcription Factors 12%