TY - JOUR
T1 - Single wavelength measurements of absorption coefficients based on iso-pathlength point
AU - Feder, Idit
AU - Duadi, Hamootal
AU - Fixler, Dror
N1 - Publisher Copyright:
© 2020 Optical Society of America under the terms of the OSA Open Access Publishing Agreement
PY - 2020/10/1
Y1 - 2020/10/1
N2 - In optical sensing, to reveal the chemical composition of tissues, the main challenge is isolating absorption from scattering. Most techniques use multiple wavelengths, which adds an error due to the optical pathlength differences. We suggest using a unique measurement angle for cylindrical tissues, the iso-pathlength (IPL) point, which depends on tissue geometry only (specifically the effective radius). We present a method for absorption assessment from a single wavelength at multiple measurement angles. The IPL point presented similar optical pathlengths for different tissues, both in simulation and experiments, hence it is optimal. Finally, in vivo measurements validated our proposed method.
AB - In optical sensing, to reveal the chemical composition of tissues, the main challenge is isolating absorption from scattering. Most techniques use multiple wavelengths, which adds an error due to the optical pathlength differences. We suggest using a unique measurement angle for cylindrical tissues, the iso-pathlength (IPL) point, which depends on tissue geometry only (specifically the effective radius). We present a method for absorption assessment from a single wavelength at multiple measurement angles. The IPL point presented similar optical pathlengths for different tissues, both in simulation and experiments, hence it is optimal. Finally, in vivo measurements validated our proposed method.
UR - http://www.scopus.com/inward/record.url?scp=85092745181&partnerID=8YFLogxK
U2 - 10.1364/BOE.401591
DO - 10.1364/BOE.401591
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C2 - 33149984
AN - SCOPUS:85092745181
SN - 2156-7085
VL - 11
SP - 5760
EP - 5771
JO - Biomedical Optics Express
JF - Biomedical Optics Express
IS - 10
ER -