Single-walled carbon nanotube coated antibacterial paper: Preparation and mechanistic study

Archana R. Deokar, Lih Yuan Lin, Chun Chao Chang, Yong Chien Ling

Research output: Contribution to journalArticlepeer-review

80 Scopus citations

Abstract

Development of carbon nanotubes toward commercial antibacterial applications warrants the understanding of their interaction mechanism with bacterial cells. The antibacterial activity and mechanism of acid-functionalized single-walled carbon nanotube (AFSWCNT) coated paper was assessed for gram-positive Staphylococcus aureus and gram-negative Escherichia coli models of bacteria. Better activity towards gram-positive bacteria was observed, whereas the presence of an outer membrane makes gram-negative bacteria more resistant to cell membrane damage caused by AFSWCNTs. Based on measured cytoplasmic efflux materials of bacteria, X-ray photoelectron spectroscopy, and scanning transmission electron microscopy combined with electron energy-loss spectroscopy imaging studies, we found that the better antibacterial activity of AFSWCNTs toward gram-positive bacteria is attributed to not only direct physical contact and piercing action, but also molecular-scale interaction with surface functional groups of bacteria. The novel antibacterial mechanism of AFSWCNTs might bring a promising strategy to design new antibacterial materials against drug-resistant bacteria species.

Original languageEnglish
Pages (from-to)2639-2646
Number of pages8
JournalJournal of Materials Chemistry B
Volume1
Issue number20
DOIs
StatePublished - 28 May 2013
Externally publishedYes

Fingerprint

Dive into the research topics of 'Single-walled carbon nanotube coated antibacterial paper: Preparation and mechanistic study'. Together they form a unique fingerprint.

Cite this