Abstract
Traditionally, gene expression measurements were performed on "bulk" samples containing populations of thousands of cells. Recent advances in genomic technology have made it possible to measure gene expression in hundreds of individual cells at a time. As a result, cellular properties that were previously masked in "bulk" measurements can now be observed directly. In this review we will survey emerging technologies for single cell transcriptomics, and describe how they are used to study complex disease such as cancer, as well as other biological phenomena such as tissue regeneration, embryonic development, and immune response.
| Original language | English |
|---|---|
| Article number | 53 |
| Journal | Frontiers in Oncology |
| Volume | 5 |
| Issue number | FEB |
| DOIs | |
| State | Published - 2015 |
Bibliographical note
Publisher Copyright:© 2015 Kanter and Kalisky.
Keywords
- FISH
- Gene expression
- RNA sequencing
- Single cell
- qPCR
