SERS nanotags for point of care diagnostics

Michael J. Natan, R. Griffith Freeman, William Doering

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

An unmet need in point-of-care diagnostics is to develop tests that perform on par with the central laboratory. Oxonica has developed a series of nanoscale optical detection tags based on surface enhanced Raman scattering (SERS) that can potentially meet these criteria. These glass-coated, reporter-loaded gold nanoparticles are excited in the near-infrared, allowing detection in complex matrices that exhibit significant background, and multiple types can simultaneously be quantified using a portable reader. This paper describes the design strategy, construction and characterization of these novel nanomaterials. Data are presented that highlight the advantages of SERS nanotags as optical labels, and use of these materials in biological applications is presented.

Original languageEnglish
Title of host publication2007 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2007, Technical Proceedings
Pages449-452
Number of pages4
StatePublished - 2007
Externally publishedYes
Event2007 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2007 - Santa Clara, CA, United States
Duration: 20 May 200724 May 2007

Publication series

Name2007 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2007, Technical Proceedings
Volume2

Conference

Conference2007 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2007
Country/TerritoryUnited States
CitySanta Clara, CA
Period20/05/0724/05/07

Keywords

  • Bioassays
  • Diagnostics
  • Nanoparticles
  • Point-of-care
  • SERS

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