TY - JOUR
T1 - Self calibration iso-pathlength point in cylindrical tissue geometry
T2 - Solution of steady-state photon diffusion based on the extrapolated zero-boundary
AU - Duadi, Hamootal
AU - Piao, Daqing
AU - Fixler, Dror
N1 - Publisher Copyright:
© 2018 Optical Society of America under the terms of the OSA Open Access Publishing Agreement.
PY - 2019/1/15
Y1 - 2019/1/15
N2 - Near-infrared optical techniques permit tissue diagnosis by surface measurement. However, the geometrical shape of this interface profiles the intensity of the surface measurement, which is found to have an iso-pathlength (IPL) point allowing for absorption identification independent of tissue scattering. The IPL point was projected in Monte Carlo (MC) simulation, validated experimentally in cylindrical tissues, but remains under-appreciated through analytical approaches. In this work, we present an analytical solution of an IPL point for steady-state diffusion based on the extrapolated zero-boundary condition. The same IPL points were found when comparing this solution to 3-D MC simulations for a tissue radius range of 5-8mm.
AB - Near-infrared optical techniques permit tissue diagnosis by surface measurement. However, the geometrical shape of this interface profiles the intensity of the surface measurement, which is found to have an iso-pathlength (IPL) point allowing for absorption identification independent of tissue scattering. The IPL point was projected in Monte Carlo (MC) simulation, validated experimentally in cylindrical tissues, but remains under-appreciated through analytical approaches. In this work, we present an analytical solution of an IPL point for steady-state diffusion based on the extrapolated zero-boundary condition. The same IPL points were found when comparing this solution to 3-D MC simulations for a tissue radius range of 5-8mm.
UR - http://www.scopus.com/inward/record.url?scp=85064410855&partnerID=8YFLogxK
U2 - 10.1364/OSAC.2.000092
DO - 10.1364/OSAC.2.000092
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AN - SCOPUS:85064410855
SN - 2578-7519
VL - 2
SP - 92
EP - 98
JO - OSA Continuum
JF - OSA Continuum
IS - 1
ER -