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Selection of spermatozoa with normal nuclei to improve the pregnancy rate with intracytoplasmic sperm injection [5]

  • Benjamin Bartoov
  • , Arie Berkovitz
  • , Fina Eltes
  • Bar-Ilan University

Research output: Contribution to journalLetterpeer-review

215 Scopus citations

Abstract

To the Editor: Intracytoplasmic injection of sperm is the recommended treatment for male infertility, associated with an average pregnancy rate per cycle of about 30 percent.1 Although sperm count and motility were found to have no effect on the outcome of intracytoplasmic sperm injection,2 scanning and transmission electron microscopy indicated that the achievement of pregnancy may depend on normal morphology of the sperm nucleus.3 We therefore introduced the motile-sperm organelle-morphology examination (MSOME), by which the fine nuclear morphology of motile spermatozoa is examined in real time with an inverted light microscope equipped with high-power differential interference contrast (Nomarski/DIC) optics (magnification, . . .
Original languageEnglish
Pages (from-to)1067-1068
Number of pages2
JournalNew England Journal of Medicine
Volume345
Issue number14
DOIs
StatePublished - 4 Oct 2001

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