Segmental conformational disorder and dynamics in the intrinsically disordered protein α-synuclein and its chain length dependence

Keyphrases

• Diffusion Coefficient 100%
• Conformational Dynamics 100%
• Alpha-synuclein (α-syn) 100%
• Intrinsically Disordered Proteins 100%
• Chain-length Dependence 100%
• Conformational Diseases 100%
• Chain Segment 75%
• End-to-end Distance 50%
• NAC Domain 50%
• Low Molecular Weight 25%
• N-terminal Domain 25%
• Order of Magnitude 25%
• Energy Transfer Analysis 25%
• Partially Overlapped 25%
• Power Law 25%
• Initiation Site 25%
• Conformational Ensemble 25%
• Polypeptide 25%
• Disordered State 25%
• Amyloid Structure 25%
• N-terminus 25%
• Structural Disorder 25%
• Chain Length 25%
• Conformational Heterogeneity 25%
• Two-segment 25%
• Coefficient of Variation 25%
• Bond Rotation 25%
• Cumulative Contribution 25%
• Short Chain 25%
• Excluded Volume Effect 25%
• Amyloid Aggregates 25%
• Conformity Bias 25%
• Neurological Degenerative Diseases 25%
• Transient Property 25%
• Protein Refolding 25%
• Natural Polypeptides 25%
• Folding Behavior 25%
• Single-molecule Fluorescence Resonance Energy Transfer (smFRET) 25%

Biochemistry, Genetics and Molecular Biology

• Intrinsically Disordered Protein 100%
• Dynamics 100%
• Diffusion Coefficient 100%
• Synuclein 100%
• Amyloid 75%
• N-Terminus 50%
• Fluorescence Resonance Energy Transfer 25%
• Conformational Ensembles 25%
• Molecular Weight 25%
• Protein Refolding 25%

Neuroscience

• Synuclein 100%
• Amyloid 100%
• Intrinsically Disordered Protein 100%
• Behavior (Neuroscience) 66%
• Polypeptide 66%
• Amino Terminal Sequence 66%
• Energy Transfer 33%
• Protein Refolding 33%