Role of a single amino acid substitution of VP3 H142D for increased acid resistance of foot-and-mouth disease virus serotype A

Keyphrases

• Single Amino Acid Substitution 100%
• Acid Resistance 100%
• Foot-and-mouth Disease Virus 100%
• Foot-and-mouth Disease Virus Serotype O 100%
• Serotype A 100%
• Dissociation 40%
• Amino Acid Residues 40%
• Enhanced Resistance 40%
• Virus-like Particles 40%
• Mutant Virus 40%
• FMD Vaccine 40%
• Resistance to Acid 40%
• Virus 20%
• PH Value 20%
• Manufacturing Process 20%
• Genetic Approach 20%
• Molecular Determinants 20%
• Endosome 20%
• Genome Size 20%
• Acid Activation 20%
• Receptor-mediated Endocytosis 20%
• Vaccine Strain 20%
• In-use 20%
• Infectivity 20%
• Dissociation Mechanism 20%
• CDNA Clone 20%
• Competition Experiments 20%
• Non-infectious 20%
• Virus Genome 20%
• Pentamer 20%
• Acidic Conditions 20%
• Reverse Genetics 20%
• Replication Ability 20%
• Resistant Phenotypes 20%
• Antigenicity 20%
• Full Genome 20%
• Capsid Protein 20%
• Acid Stability 20%
• Acid Inactivation 20%
• VP3 Protein 20%
• Virus Competition 20%

Immunology and Microbiology

• Amino Acid Substitution 100%
• Serotype 100%
• Foot and Mouth Disease Virus 100%
• Vaccine Efficacy 42%
• Virus Particle 28%
• Virus Mutant 28%
• Antigenicity 14%
• Virus Genome 14%
• Capsid 14%
• Endocytosis 14%
• Functional Dissociation 14%
• Endosome 14%
• Molecular Cloning 14%