Abstract
Oxidative alkaline cleavage of the title compound 3 gave unexpectedly in high yields the α-keto acid 9a instead of the aldehyde acid 5 (or its tautomer 7). The latter could be prepared via regioselective mono-ketalisation of compound 3. The structure assignment of 9, and differentiation between 5/7 and the isomer 10, were effected using natural abundance 13C13C coupling techniques.
Original language | English |
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Pages (from-to) | 3775-3776 |
Number of pages | 2 |
Journal | Tetrahedron Letters |
Volume | 27 |
Issue number | 32 |
DOIs | |
State | Published - 1986 |
Externally published | Yes |