Review: Remotely controlled magneto-regulation of therapeutics from magnetoelastic gel matrices

Sayan Ganguly, Shlomo Margel

Research output: Contribution to journalReview articlepeer-review

43 Scopus citations

Abstract

Surface active magnetic nanoparticles especially superparamagnetic iron oxides are already occupying a major domain in medical therapeutics. Arresting of these magnetic nanoparticles into polymer hydrogel is a spatial assembly of nanoparticles that serves the precise delivery of drug molecules. Magnetic hydrogels are very less cultured area still in the biomedical field. This review embraces how the external magnetic field (either static or oscillating) affects the payload release from the hydrogel matrix and their magneto-regulative deformation. Besides these, we also discussed how the ferrosponge and biphasic ferrogel based scaffold type systems impact over the release kinetics and tunability of drug release behaviours.

Original languageEnglish
Article number107611
JournalBiotechnology Advances
Volume44
DOIs
StatePublished - 15 Nov 2020

Bibliographical note

Publisher Copyright:
© 2020 Elsevier Inc.

Keywords

  • Biphasic
  • Drug release
  • Ferrosponge
  • Magneto-regulative deformation
  • Medical therapeutics
  • Polymer hydrogel
  • Superparamagnetic

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