Replicative Intermediates of Ram Sperm Mitochondrial DNA

J. Fisher, B. Bartoov

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Replication of mtDNA from ejaculated ram spermatozoa was demonstrated by electron microscopy. Twelve percent of mtDNA circular molecules isolated either from ram sperm cells or from rat liver mitochondria were double-forked. These replicative intermediates appeared in four distinct steps of replication: 3.9%, 21.0%, 27.8%, and 44% of the circular contour length. The biological significance of sperm mitochondrial DNA replication is discussed.

Original languageEnglish
Pages (from-to)341-346
Number of pages6
JournalArchives of Andrology
Issue number4
StatePublished - Jan 1980


  • Ram spermatozoa
  • Replication
  • Sperm mitochondria
  • mtDNA


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