Renal and systemic effects of chronic blockade of ET_A or ET _B in normal rats and animals with experimental heart failure

Keyphrases

• Congestive Heart Failure 100%
• Systemic Effects 100%
• Renal Effects 100%
• Preclinical Heart Failure 100%
• Endothelin-1 (ET-1) 71%
• Renal Vasoconstriction 57%
• Sodium Excretion 42%
• Chronic Treatment 28%
• Sham Control 28%
• Mean Arterial Pressure 28%
• Endothelin B Receptor 28%
• Receptor-mediated 14%
• Natriuresis 14%
• Beta-blockers 14%
• Na+ Retention 14%
• Osmotic Minipump 14%
• Hemodynamic Changes 14%
• Chronic Administration 14%
• Acute Administration 14%
• Aortocaval Fistula 14%
• Renal Hemodynamics 14%
• Cardiac Hypertrophy 14%
• Vasodilation 14%
• Cardiac Hemodynamics 14%
• Hypotensive Effect 14%
• Excretory Function 14%
• Endothelin B 14%

Medicine and Dentistry

• Congestive Heart Failure 100%
• Experimental Heart Failure 100%
• Endothelin 1 57%
• Vasoconstriction 57%
• Sodium Excretion 42%
• 4 (1,3 Benzodioxol 5 Yl) 1 [(2,6 Diethylphenyl)carbamoylmethyl] 2 (4 Propoxyphenyl) 3 Pyrrolidinecarboxylic Acid 42%
• Mean Arterial Pressure 28%
• Endothelin B Receptor 28%
• Endothelin 28%
• Sodium Ion 14%
• Kidney Blood Flow 14%
• Excretion 14%
• Natriuresis 14%
• Salicylate Sodium 14%
• Vasodilatation 14%
• Aortocaval Fistula 14%
• Ventricular Hypertrophy 14%
• Acute Drug Administration 14%
• Heart Hemodynamics 14%
• Chronic Drug Administration 14%

Pharmacology, Toxicology and Pharmaceutical Science

• Congestive Heart Failure 100%
• Experimental Heart Failure 100%
• Endothelin 1 57%
• 4 (1,3 Benzodioxol 5 Yl) 1 [(2,6 Diethylphenyl)carbamoylmethyl] 2 (4 Propoxyphenyl) 3 Pyrrolidinecarboxylic Acid 42%
• Endothelin B Receptor 28%
• Endothelin 28%
• Salicylate Sodium 14%
• Sodium Ion 14%
• Heart Ventricle Hypertrophy 14%
• Aortocaval Fistula 14%