Remote photoacoustic sensing using speckle-analysis

Benjamin Lengenfelder, Fanuel Mehari, Martin Hohmann, Markus Heinlein, Erika Chelales, Maximilian J. Waldner, Florian Klämpfl, Zeev Zalevsky, Michael Schmidt

Research output: Contribution to journalArticlepeer-review

21 Scopus citations

Abstract

Laser surgery is a rising surgical technique, which offers several advantages compared to the traditional scalpel. However, laser surgery lacks a contact-free feedback system which offers high imaging contrast to identify the tissue type ablated and also a high penetration depth. Photoacoustic imaging has the potential to fill this gap. Since photoacoustic detection is commonly contact based, a new non-interferometric detection technique based on speckle-analysis for remote detection is presented in this work. Phantom and ex-vivo experiments are carried out in transmission and reflection-mode for proof of concept. In summary, the potential of the remote speckle sensing technique for photoacoustic detection is demonstrated. In future, this technique might be applied for usage as a remote feedback system for laser surgery, which could help to broaden the applications of lasers as smart surgical tools.

Original languageEnglish
Article number1057
JournalScientific Reports
Volume9
Issue number1
DOIs
StatePublished - 1 Dec 2019

Bibliographical note

Funding Information:
The authors would like to thank the German Research Foundation (DFG–Deutsche Forschungsgemeinschaft) for their support. Parts of this work were achieved in the context of the DFG-project ‘Kontaktlose photoakustische Bildgebung von Gewebe’ (Project Number 397972545). Also funding of the Erlangen Graduate School in Advanced Optical Technologies (SAOT) in the framework of the German excellence initiative is gratefully acknowledged.

Publisher Copyright:
© 2019, The Author(s).

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