TY - JOUR
T1 - Relationship between anticomplement in seminal plasma and complement in follicular fluid associated with outcome in an in vitro fertilization program
AU - Zabludovsky, Natalia
AU - Barak, Yona
AU - Bartoov, Benjamin
AU - Lublin-Tennenbaum, Tamar
AU - Eltes, Fina
AU - Amit, Ami
AU - Kogosowski, Abraham
PY - 1996/7
Y1 - 1996/7
N2 - Purpose: The study was conducted to evaluate levels of anticomplement in seminal plasma and levels of complement in follicular fluid, in correlation with fertilization and pregnancy rate after in vitro fertilization and intracytoplasmic sperm injection programs. Materials and Methods: Anticomplement levels were determined in 70 couples undergoing in vitro fertilization therapy. In 15 of these couples, complement levels were measured. Anticomplement and complement levels were also determined in an additional 21 couples (apart from the 70 couples) undergoing intracytoplasmic sperm injection treatment. Results: A correlation was found between fertilization rate and anticomplement levels in the seminal plasma (r = 0.4, P < 0.01) after standard in vitro fertilization. No correlation was found in the intracytoplasmic sperm injection group, or observed between complement levels and any parameter examined in both groups. Pregnancy occurred only in those couples with an anticomplement:complement ratio below 0.49. Conclusions: Determination of anticomplement and complement levels may contribute to the assessment of a successful outcome of in vitro fertilization/intracytoplasmic sperm injection.
AB - Purpose: The study was conducted to evaluate levels of anticomplement in seminal plasma and levels of complement in follicular fluid, in correlation with fertilization and pregnancy rate after in vitro fertilization and intracytoplasmic sperm injection programs. Materials and Methods: Anticomplement levels were determined in 70 couples undergoing in vitro fertilization therapy. In 15 of these couples, complement levels were measured. Anticomplement and complement levels were also determined in an additional 21 couples (apart from the 70 couples) undergoing intracytoplasmic sperm injection treatment. Results: A correlation was found between fertilization rate and anticomplement levels in the seminal plasma (r = 0.4, P < 0.01) after standard in vitro fertilization. No correlation was found in the intracytoplasmic sperm injection group, or observed between complement levels and any parameter examined in both groups. Pregnancy occurred only in those couples with an anticomplement:complement ratio below 0.49. Conclusions: Determination of anticomplement and complement levels may contribute to the assessment of a successful outcome of in vitro fertilization/intracytoplasmic sperm injection.
KW - anticomplement
KW - complement
KW - in vitro fertilization
KW - intracytoplasmic sperm injection
UR - http://www.scopus.com/inward/record.url?scp=0029891694&partnerID=8YFLogxK
U2 - 10.1007/bf02066527
DO - 10.1007/bf02066527
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C2 - 8835675
AN - SCOPUS:0029891694
SN - 1058-0468
VL - 13
SP - 472
EP - 476
JO - Journal of Assisted Reproduction and Genetics
JF - Journal of Assisted Reproduction and Genetics
IS - 6
ER -