Regulatory feedback pathways in the thymus

  • Ramit Mehr
  • , Alan S. Perelson
  • , Masha Fridkis-Hareli
  • , Amiela Globerson

Research output: Contribution to journalComment/debate

33 Scopus citations

Abstract

The idea that thymocytopoiesis may be subject to feedback regulation by mature lymphocytes is proposed on the basis of recent data from in vitro experimental models. Analysis of the data using mathematical models, presented here by Ramit Mehr and colleagues, suggests possible feedback control mechanisms in T-cell development.

Original languageEnglish
Pages (from-to)581-585
Number of pages5
JournalImmunology Today
Volume18
Issue number12
DOIs
StatePublished - Dec 1997
Externally publishedYes

Funding

FundersFunder number
National Institute of Allergy and Infectious DiseasesR01AI028433

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