Regulation of Caenorhabditis elegans lifespan by a proteasomal E3 ligase complex

Keyphrases

• Caenorhabditis Elegans 100%
• E3 Ligase 100%
• DAF-16 66%
• Aging 33%
• Biological Processes 33%
• Transcriptional Activity 33%
• Transcription Factor 33%
• Nuclear Accumulation 33%
• Extended Life 33%
• Insulin 33%
• Insulin-like 33%
• Growth Factors 33%
• Complex Function 33%
• Regulatory Capacity 33%
• Specificity Protein 1 33%
• Cellular Homeostasis 33%
• Post-mitotic 33%
• Genetic Determination 33%
• CUL1 33%
• Longevity Genes 33%
• Somatic Tissues 33%
• SKP1 33%
• Oxidized Proteins 33%
• F-box 33%
• Damaged Proteins 33%
• Controlled Breakdown 33%
• Proteasomal Pathway 33%
• Cellular Pathways 33%

Biochemistry, Genetics and Molecular Biology

• Lifespan 100%
• Caenorhabditis Elegans 100%
• Ligase 100%
• Proteasome 50%
• Genetics 25%
• Skp1 25%
• Biological Phenomena and Functions Concerning the Entire Organism 25%
• Homeostasis 25%
• Transcription Factor FOXO 25%
• Insulin-Like Growth Factor 1 25%