Reflected light intensity profile of two-layer tissues: Phantom experiments

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Abstract

Experimental measurements of the reflected light intensity from two-layer phantoms are presented. We report, for the first time, an experimental observation of a typical reflected light intensity behavior for the two-layer structure characterized by two different slopes in the reflected light profile of the irradiated tissue. The point in which the first slope changes to the second slope, named as the crossover point, depends on the upper layer thickness as well as on the ratio between the absorption coefficients of the two layers. Since similar experiments from one-layer phantoms present a monotonic decay behavior, the existence and the location of the crossover point can be used as a diagnostic fingerprint for two-layer tissue structures. This pertains to two layers with greater absorptivity in the upper layer, which is the typical biological case in tissues like skin.

Original languageEnglish
Article number085001
JournalJournal of Biomedical Optics
Volume16
Issue number8
DOIs
StatePublished - Aug 2011

Keywords

  • Biological structures
  • Phantom experiments
  • Photon migration
  • Reflected light intensity measurements
  • Two-layer tissues

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