Refining immunotherapeutic approaches to high-risk neuroblastoma based on tumor genomic profiles

Research output: Contribution to journalComment/debate

Abstract

In this issue, Coronado et al. attempt to improve our understanding of the factors affecting the response to immunotherapy in a large subset of high-risk neuroblastoma with hemizygous deletion of chromosome 11q. By using several computational approaches, the authors study potential transcriptional and post-transcriptional pathways that may affect the response to immunotherapy and further be leveraged therapeutically in a biomarker-directed fashion.

Original languageEnglish
Pages (from-to)347-349
Number of pages3
JournalMolecular Oncology
Volume15
Issue number2
DOIs
StatePublished - Feb 2021
Externally publishedYes

Bibliographical note

Publisher Copyright:
© 2020 The Authors. Published by FEBS Press and John Wiley & Sons Ltd.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • 11q deletion
  • anti-GD2 therapy
  • immune checkpoint inhibition
  • microRNAs

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