Real-Time In Vivo Monitoring of Cellular Energy Metabolism

Avraham Mayevsky, Efrat Barbiro-Michaely

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

Tissue oxygen or energy positive balance is necessary for the required level of ATP production by mitochondria. The majority of oxygen in a mammalian organism is delivered to cells by erythrocytes: it diffuses along the partial pressure gradient from the lungs (100 mm Hg) to the bloodstream, where it combines chemically to hemoglobin (Hb) in erythrocytes and is carried by convective transport through the large vessels down to arterioles and capillaries. Smaller pressure near the mitochondria (1 mm Hg) favors oxygen diffusion from the microcirculation compartments into the cells (Figure 6.1).

Original languageEnglish
Title of host publicationNatural Biomarkers for Cellular Metabolism
Subtitle of host publicationBiology, Techniques, and Applications
PublisherCRC Press
Pages137-155
Number of pages19
ISBN (Electronic)9781466509993
DOIs
StatePublished - 1 Jan 2014

Bibliographical note

Publisher Copyright:
© 2015 by Taylor and Francis Group, LLC.

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