Rational design of vaccine targets and strategies for HIV: A crossroad of statistical physics, biology, and medicine

Arup K. Chakraborty, John P. Barton

Research output: Contribution to journalReview articlepeer-review

16 Scopus citations

Abstract

Vaccination has saved more lives than any other medical procedure. Pathogens have now evolved that have not succumbed to vaccination using the empirical paradigms pioneered by Pasteur and Jenner. Vaccine design strategies that are based on a mechanistic understanding of the pertinent immunology and virology are required to confront and eliminate these scourges. In this perspective, we describe just a few examples of work aimed to achieve this goal by bringing together approaches from statistical physics with biology and clinical research.

Original languageEnglish
Article number032601
JournalReports on Progress in Physics
Volume80
Issue number3
DOIs
StatePublished - Mar 2017
Externally publishedYes

Bibliographical note

Publisher Copyright:
© 2017 IOP Publishing Ltd.

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