Rapid and simple detection of sodium thiocyanate in milk using surface-enhanced Raman spectroscopy based on silver aggregates

Xiang Lin, Wu Li Ji Hasi, Xiu Tao Lou, Shuang Lin, Fang Yang, Bao Shen Jia, Yu Cui, De Xin Ba, Dian Yang Lin, Zhi Wei Lu

Research output: Contribution to journalArticlepeer-review

44 Scopus citations

Abstract

Surface-enhanced Raman spectroscopy (SERS) was used for rapid detection of sodium thiocyanate in milk employing silver aggregates as active substrate. Silver nanoparticles were induced to silver aggregates by trichloroacetic acid (TCA). The limit of detection (LOD) for sodium thiocyanate was 10-2 g ml-1 in water with an analytical enhancement factor of 5.4 × 106. The silver aggregates represent good reproducibility and stability. Good linear relationship was obtained for sodium thiocyanate in milk at concentration ranges from 0.1 to 10 g ml-1 (R2 = 0.995). Using TCA as protein precipitator, silver colloid would aggregate spontaneously when mixing with samples during SERS measurement without the need of additional aggregating agent. The simple pretreatment procedures and analytical methods are less time consuming (<10 min) and environmentally friendly, making the proposed method much practical for in situ detection of sodium thiocyanate in market milk.

Original languageEnglish
Pages (from-to)162-167
Number of pages6
JournalJournal of Raman Spectroscopy
Volume45
Issue number2
DOIs
StatePublished - Feb 2014
Externally publishedYes

Keywords

  • 42.65.-k
  • 42.65.Es
  • SERS
  • milk
  • silver aggregates
  • sodium thiocyanate
  • trichloroacetic acid

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