Randomized trial of compression duration after transradial cardiac catheterization and intervention

Shahar Lavi, Asim Cheema, Andrew Yadegari, Zeev Israeli, Yaniv Levi, Sabrina Wall, Mistre Alemayehu, Yasir Parviz, Bogdan Dorian Murariu, Terry McPherson, Jaffer Syed, Rodrigo Bagur

Research output: Contribution to journalArticlepeer-review

30 Scopus citations


Background-Radial artery occlusion is a known complication following transradial cardiac catheterization. A shorter duration of postprocedural radial clamp time may reduce radial artery occlusion (RAO) but might be associated with incomplete hemostasis. Methods and Results-In total, 568 patients undergoing transradial diagnostic cardiac catheterization were randomly assigned to either 20 minutes (ultrashort) or 60 minutes (short) hemostatic compression time using patent hemostasis. Subsequently, clamp pressure was reduced gradually over 20 minutes. Access site hemostasis and RAO were assessed after clamp removal. Repeated assessment of RAO was determined at 1 week in 210 (37%) patients. Mean age was 64±11 years, and 30% were female. Percutaneous coronary intervention was performed in 161 patients. RAO immediately after clamp removal was documented in 14 (4.9%) and 8 (2.8%) patients in the 20-and 60-minute clamp application groups, respectively (P=0.19). The incidence of grade 1 hematoma was higher in the 20-minute group (6.7% versus 2.5%, P=0.015). RAO at 1 week after the procedure was 2.9% and 0.9% in the 20-and 60-minute groups, respectively (P=0.36). Requirement for clamp retightening (36% versus 16%, P=0.01) was higher among patients who had RAO. Need for clamp retightening was the only independent predictor of RAO (P=0.04). Conclusions-Ultrashort radial clamp application of 20 minutes is not preferable to a short duration of 60 minutes. The 60-minute clamp duration is safe and provides good access site hemostasis with low RAO rates.

Original languageEnglish
Article numbere005029
JournalJournal of the American Heart Association
Issue number2
StatePublished - 3 Feb 2017
Externally publishedYes

Bibliographical note

Publisher Copyright:
© 2017 The Authors.


  • Angiography
  • Cardiac catheterization
  • Percutaneous coronary intervention
  • Vascular complications


Dive into the research topics of 'Randomized trial of compression duration after transradial cardiac catheterization and intervention'. Together they form a unique fingerprint.

Cite this