Abstract
This study highlights the potential application of antimicrobial quaternary ammonium nanomaterials for water disinfection. Quaternary ammonium polyethylenimine (QA-PEI) nanoparticles (NPs) were synthesized by polyethylenimine crosslinking and alkylation with octyl iodide followed by methyl iodide quaternization. Particles modified with octyldodecyl alkyl chains were also prepared and evaluated. The antimicrobial activity of QA-PEI NPs was studied after anchoring in non-leaching polymeric coatings and also in aqueous suspension. Particles at different loadings (w/w) were embedded in polyethylene vinyl acetate and polyethylene methacrylic acid coatings and tested for antimicrobial activity against four representative strains of bacteria in static and dynamic modes. Coatings embedded with fluorescent labelled particles tracked by Axioscope fluorescence microscope during the antimicrobial test indicates no particles leaching out. Coatings loaded with 5% w/w QA-PEI exhibited strong antibacterial activity. Aqueous suspension was tested and found effective for bacterial decontamination at 0.1. ppm and maintains its activity for several weeks.
| Original language | English |
|---|---|
| Pages (from-to) | 614-619 |
| Number of pages | 6 |
| Journal | Colloids and Surfaces B: Biointerfaces |
| Volume | 128 |
| DOIs | |
| State | Published - 1 Apr 2015 |
| Externally published | Yes |
Bibliographical note
Publisher Copyright:© 2015 Elsevier B.V.
Keywords
- Antimicrobial nanoparticles
- Antimicrobial surface
- Polyethylenimine
- Water disinfection