Quaternary ammonium antimicrobial polymers

Abraham J. Domb, Nurit Beyth, Shady Farah

Research output: Contribution to journalConference articlepeer-review

4 Scopus citations


Polymers possessing antimicrobial activity have been used for self sterilization surfaces as well as agents for treating contaminated water. Cationic polymers based on quaternary ammonium or guanidine groups have shown high inherent antimicrobial activity where the activity is related to the disruption of the microorganism cell wall. A range of antimicrobial nanoparticles possessing active quaternary ammonium groups with one of the alkyl is a an octyl chain have been synthesized. These nanoparticles were incorporated in dental restoration compositions to form self sterile composites. Quaternary ammonium polyethyleneimine nanoparticles with N-octyl dimethyl residues, demonstrated high antibacterial effect.

Original languageEnglish
JournalMaterials Research Society Symposium - Proceedings
StatePublished - 2013
Externally publishedYes
Event2013 MRS Spring Meeting - San Francisco, CA, United States
Duration: 1 Apr 20135 Apr 2013


  • Biomaterial
  • Nanostructure
  • Polymerization


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