Pyridoxal derived chemosensor for chromogenic sensing of Cu2+ and fluorogenic sensing of Fe3+ in semi-aqueous medium

Suban K. Sahoo, Darshna Sharma, Anuradha Moirangthem, Aman Kuba, Rini Thomas, Rajender Kumar, Anil Kuwar, Heung Jin Choi, Anupam Basu

Research output: Contribution to journalArticlepeer-review

65 Scopus citations

Abstract

An easy-to-prepare chemosensor L was developed by condensation of pyridoxal with 1,8-diaminonaphthalene. In DMSO:H2O (1:1, v/v), sensor L displayed a highly selective and sensitive response towards Cu2+ via perceptible color and UV-vis absorbance changes among the other tested metal ions. However, the fluorescence of L is selectively quenched in the presence of both Fe3+ and Cu2+. With a micromolar detection limit and non-interference from other co-existing metal ions, this sensor can be applied over a wide pH range for the detection of Fe3+ and Cu2+. In addition, the cytotoxicity and fluorescence changes of L within live HeLa cells were examined in the absence and presence of Cu2+.

Original languageEnglish
Pages (from-to)297-303
Number of pages7
JournalJournal of Luminescence
Volume172
DOIs
StatePublished - 1 Apr 2016
Externally publishedYes

Bibliographical note

Publisher Copyright:
© 2015 Elsevier B.V. All rights reserved.

Keywords

  • Colorimetric and fluorescence sensor
  • Cu
  • Cytotoxicity
  • Fe
  • Pyridoxal derivative

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