Pyridoxal derived chemosensor for chromogenic sensing of Cu2+ and fluorogenic sensing of Fe3+ in semi-aqueous medium

Suban K. Sahoo; Darshna Sharma; Anuradha Moirangthem; Aman Kuba; Rini Thomas; Rajender Kumar; Anil Kuwar; Heung Jin Choi; Anupam Basu

doi:10.1016/j.jlumin.2015.12.035

Pyridoxal derived chemosensor for chromogenic sensing of Cu²⁺ and fluorogenic sensing of Fe³⁺ in semi-aqueous medium

Suban K. Sahoo, Darshna Sharma, Anuradha Moirangthem, Aman Kuba, Rini Thomas, Rajender Kumar, Anil Kuwar, Heung Jin Choi, Anupam Basu

Research output: Contribution to journal › Article › peer-review

68 Scopus citations

Abstract

An easy-to-prepare chemosensor L was developed by condensation of pyridoxal with 1,8-diaminonaphthalene. In DMSO:H₂O (1:1, v/v), sensor L displayed a highly selective and sensitive response towards Cu²⁺ via perceptible color and UV-vis absorbance changes among the other tested metal ions. However, the fluorescence of L is selectively quenched in the presence of both Fe³⁺ and Cu²⁺. With a micromolar detection limit and non-interference from other co-existing metal ions, this sensor can be applied over a wide pH range for the detection of Fe³⁺ and Cu²⁺. In addition, the cytotoxicity and fluorescence changes of L within live HeLa cells were examined in the absence and presence of Cu²⁺.

Original language	English
Pages (from-to)	297-303
Number of pages	7
Journal	Journal of Luminescence
Volume	172
DOIs	https://doi.org/10.1016/j.jlumin.2015.12.035
State	Published - 1 Apr 2016
Externally published	Yes

Bibliographical note

Publisher Copyright:
© 2015 Elsevier B.V. All rights reserved.

Funding

The authors wish to thank the Director, S.V. National Institute of Technology, Surat for providing necessary facilities and scholarship. This work was made possible by a grant from the DST SERB, New Delhi (SR/S1/IC-54/2012).

Funders	Funder number
DST SERB	SR/S1/IC-54/2012

Keywords

Colorimetric and fluorescence sensor
Cu
Cytotoxicity
Fe
Pyridoxal derivative

Access to Document

10.1016/j.jlumin.2015.12.035

Cite this

@article{a64edc8bf21548258240291675445eb9,

title = "Pyridoxal derived chemosensor for chromogenic sensing of Cu2+ and fluorogenic sensing of Fe3+ in semi-aqueous medium",

abstract = "An easy-to-prepare chemosensor L was developed by condensation of pyridoxal with 1,8-diaminonaphthalene. In DMSO:H2O (1:1, v/v), sensor L displayed a highly selective and sensitive response towards Cu2+ via perceptible color and UV-vis absorbance changes among the other tested metal ions. However, the fluorescence of L is selectively quenched in the presence of both Fe3+ and Cu2+. With a micromolar detection limit and non-interference from other co-existing metal ions, this sensor can be applied over a wide pH range for the detection of Fe3+ and Cu2+. In addition, the cytotoxicity and fluorescence changes of L within live HeLa cells were examined in the absence and presence of Cu2+.",

keywords = "Colorimetric and fluorescence sensor, Cu, Cytotoxicity, Fe, Pyridoxal derivative",

author = "Sahoo, {Suban K.} and Darshna Sharma and Anuradha Moirangthem and Aman Kuba and Rini Thomas and Rajender Kumar and Anil Kuwar and Choi, {Heung Jin} and Anupam Basu",

year = "2016",

month = apr,

day = "1",

doi = "10.1016/j.jlumin.2015.12.035",

language = "אנגלית",

volume = "172",

pages = "297--303",

journal = "Journal of Luminescence",

issn = "0022-2313",

publisher = "Elsevier B.V.",

}

TY - JOUR

T1 - Pyridoxal derived chemosensor for chromogenic sensing of Cu2+ and fluorogenic sensing of Fe3+ in semi-aqueous medium

AU - Sahoo, Suban K.

AU - Sharma, Darshna

AU - Moirangthem, Anuradha

AU - Kuba, Aman

AU - Thomas, Rini

AU - Kumar, Rajender

AU - Kuwar, Anil

AU - Choi, Heung Jin

AU - Basu, Anupam

PY - 2016/4/1

Y1 - 2016/4/1

N2 - An easy-to-prepare chemosensor L was developed by condensation of pyridoxal with 1,8-diaminonaphthalene. In DMSO:H2O (1:1, v/v), sensor L displayed a highly selective and sensitive response towards Cu2+ via perceptible color and UV-vis absorbance changes among the other tested metal ions. However, the fluorescence of L is selectively quenched in the presence of both Fe3+ and Cu2+. With a micromolar detection limit and non-interference from other co-existing metal ions, this sensor can be applied over a wide pH range for the detection of Fe3+ and Cu2+. In addition, the cytotoxicity and fluorescence changes of L within live HeLa cells were examined in the absence and presence of Cu2+.

AB - An easy-to-prepare chemosensor L was developed by condensation of pyridoxal with 1,8-diaminonaphthalene. In DMSO:H2O (1:1, v/v), sensor L displayed a highly selective and sensitive response towards Cu2+ via perceptible color and UV-vis absorbance changes among the other tested metal ions. However, the fluorescence of L is selectively quenched in the presence of both Fe3+ and Cu2+. With a micromolar detection limit and non-interference from other co-existing metal ions, this sensor can be applied over a wide pH range for the detection of Fe3+ and Cu2+. In addition, the cytotoxicity and fluorescence changes of L within live HeLa cells were examined in the absence and presence of Cu2+.

KW - Colorimetric and fluorescence sensor

KW - Cu

KW - Cytotoxicity

KW - Fe

KW - Pyridoxal derivative

UR - http://www.scopus.com/inward/record.url?scp=84952360637&partnerID=8YFLogxK

U2 - 10.1016/j.jlumin.2015.12.035

DO - 10.1016/j.jlumin.2015.12.035

M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???

AN - SCOPUS:84952360637

SN - 0022-2313

VL - 172

SP - 297

EP - 303

JO - Journal of Luminescence

JF - Journal of Luminescence

ER -