TY - JOUR
T1 - Pyridine nucleotide oxidation‐reduction state of the cerebral cortex in the awake gerbil
AU - Mayevsky, Avraham
PY - 1978
Y1 - 1978
N2 - A new approach to study the effect of ischemia on the brain of the awake gerbil is described. The measurement of NADH fluorescence from the surface of the cortex is done by a time‐sharing fluorometer/reflectometer connected to the brain via a flexible light guide and an implanted cannula. The response of the gerbil brain to anoxia and spreading depression is described. By unilateral occlusion of the carotid artery and increase in NADH was measured in the ipsilateral hemisphere.
AB - A new approach to study the effect of ischemia on the brain of the awake gerbil is described. The measurement of NADH fluorescence from the surface of the cortex is done by a time‐sharing fluorometer/reflectometer connected to the brain via a flexible light guide and an implanted cannula. The response of the gerbil brain to anoxia and spreading depression is described. By unilateral occlusion of the carotid artery and increase in NADH was measured in the ipsilateral hemisphere.
KW - NADH oxidation‐reduction state
KW - brain energy metabolism
KW - ischemia in gerbil's brain
KW - spreading depression and NADH
UR - http://www.scopus.com/inward/record.url?scp=0018235218&partnerID=8YFLogxK
U2 - 10.1002/jnr.490030508
DO - 10.1002/jnr.490030508
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C2 - 216812
AN - SCOPUS:0018235218
SN - 0360-4012
VL - 3
SP - 369
EP - 374
JO - Journal of Neuroscience Research
JF - Journal of Neuroscience Research
IS - 5-6
ER -