Protein translation in mammalian sperm.

Yael Gur, Haim Breitbart

Research output: Contribution to journalArticlepeer-review

15 Scopus citations


Our recent work has shown for the first time the translation of nuclear-encoded proteins in mammalian spermatozoa. We demonstrate that several sperm proteins are degraded after a relatively long period of incubation, and some of these proteins are resynthesised when sperm were incubated under capacitation conditions. In the present study using specific antisenses we demonstrated a significant reduction in the level of several sperm proteins and inhibition of sperm motility, actin polymerization and the acrosome reaction. Thus, this study further supports our previous notion regarding the synthesis of proteins during sperm capacitation.

Original languageEnglish
Pages (from-to)391-397
Number of pages7
JournalSociety of Reproduction and Fertility supplement
StatePublished - 2007


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