Prospects of Biosensors Based on Functionalized and Nanostructured Solitary Materials: Detection of Viral Infections and Other Risks

Sanjeev Kumar, Ritika Sharma, Bhawna, Akanksha Gupta, Prashant Singh, Susheel Kalia, Pankaj Thakur, Vinod Kumar

Research output: Contribution to journalReview articlepeer-review

13 Scopus citations

Abstract

Advances in nanotechnology over the past decade have emerged as a substitute for conventional therapies and have facilitated the development of economically viable biosensors. Next-generation biosensors can play a significant role in curbing the spread of various viruses, including HCoV-2, and controlling morbidity and mortality. Pertaining to the impact of the current pandemic, there is a need for point-of-care biosensor-based testing as a detection method to accelerate the detection process. Integrating biosensors with nanostructures could be a substitute for ultrasensitive label-free biosensors to amplify sensing and miniaturization. Notably, next-generation biosensors could expedite the detection process. An elaborate description of various types of functionalized nanomaterials and their synthetic aspects is presented. The utility of the functionalized nanostructured materials for fabricating nanobiosensors to detect several types of viral infections is described in this review. This review also discusses the choice of appropriate nanomaterials, as well as challenges and opportunities in the field of nanobiosensors.

Original languageEnglish
Pages (from-to)22073-22088
Number of pages16
JournalACS Omega
Volume7
Issue number26
DOIs
StatePublished - 5 Jul 2022
Externally publishedYes

Bibliographical note

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© 2022 American Chemical Society. All rights reserved.

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