Progesterone Increases Bifidobacterium Relative Abundance during Late Pregnancy

Meital Nuriel-Ohayon, Hadar Neuman, Oren Ziv, Anna Belogolovski, Yiftah Barsheshet, Naamah Bloch, Atara Uzan, Roey Lahav, Avi Peretz, Sigal Frishman, Moshe Hod, Eran Hadar, Yoram Louzoun, Orly Avni, Omry Koren

Research output: Contribution to journalArticlepeer-review

126 Scopus citations

Abstract

Nuriel-Ohayon et al. demonstrate a dramatic shift in the gut microbial composition of women and mice during late pregnancy, including an increase in the relative abundance of Bifidobacterium. Using in vitro and in vivo experiments, they show that supplementation of progesterone affects the microbial communities, including increasing the relative abundance of Bifidobacterium.

Original languageEnglish
Pages (from-to)730-736.e3
JournalCell Reports
Volume27
Issue number3
DOIs
StatePublished - 16 Apr 2019

Bibliographical note

Publisher Copyright:
© 2019 The Author(s)

Keywords

  • 16S rRNA
  • Bifidobacterium
  • gut microbiota
  • microbiome
  • pregnancy
  • progesterone

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