TY - JOUR
T1 - Primary Oral Malignancy Imitating Peri-Implantitis
AU - Raiser, Vadim
AU - Abu-El Naaj, Immad
AU - Shlomi, Benjamin
AU - Fliss, Dan M.
AU - Kaplan, Ilana
N1 - Publisher Copyright:
© 2016 American Association of Oral and Maxillofacial Surgeons
PY - 2016/7/1
Y1 - 2016/7/1
N2 - Purpose To describe new cases of primary malignancy arising around dental implants. Materials and Methods Three patients presented with asymptomatic lesions around longstanding dental implants that resembled peri-implantitis. One case was primary large B-cell lymphoma and the remaining cases were primary squamous cell carcinoma in patients with oral lichen planus. The literature was reviewed for cases mimicking peri-implantitis. Results Of 42 implant-associated malignancies reported from 2000 through 2014, 85.7% were squamous cell carcinoma (69% primary and 9.4% metastatic). Most patients presented with pre-existing risk factors for oral cancer. Lymphoma was not associated with dental implants. Conclusions Primary and metastatic malignancies can occur in peri-implant mucosa, often with clinical and radiographic features resembling peri-implantitis. Clinicians should have a high index of suspicion for changes in peri-implant mucosa in patients with existing risk factors; however, rare cases such as lymphoma might present outside this risk population. Histopathologic analysis should be included in the management of selected peri-implant lesions to avoid delayed diagnosis of malignancy.
AB - Purpose To describe new cases of primary malignancy arising around dental implants. Materials and Methods Three patients presented with asymptomatic lesions around longstanding dental implants that resembled peri-implantitis. One case was primary large B-cell lymphoma and the remaining cases were primary squamous cell carcinoma in patients with oral lichen planus. The literature was reviewed for cases mimicking peri-implantitis. Results Of 42 implant-associated malignancies reported from 2000 through 2014, 85.7% were squamous cell carcinoma (69% primary and 9.4% metastatic). Most patients presented with pre-existing risk factors for oral cancer. Lymphoma was not associated with dental implants. Conclusions Primary and metastatic malignancies can occur in peri-implant mucosa, often with clinical and radiographic features resembling peri-implantitis. Clinicians should have a high index of suspicion for changes in peri-implant mucosa in patients with existing risk factors; however, rare cases such as lymphoma might present outside this risk population. Histopathologic analysis should be included in the management of selected peri-implant lesions to avoid delayed diagnosis of malignancy.
UR - http://www.scopus.com/inward/record.url?scp=84963956143&partnerID=8YFLogxK
U2 - 10.1016/j.joms.2016.02.008
DO - 10.1016/j.joms.2016.02.008
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C2 - 26973225
AN - SCOPUS:84963956143
SN - 0278-2391
VL - 74
SP - 1383
EP - 1390
JO - Journal of Oral and Maxillofacial Surgery
JF - Journal of Oral and Maxillofacial Surgery
IS - 7
ER -