Prevention of LVOT Obstruction by Device-Mediated Laceration of the Anterior Mitral Valve Leaflet During TMVR

Sebastian Ludwig; Daniel Kalbacher; Lara Waldschmidt; Andreas Schaefer; Thomas Modine; Danny Dvir; Shemy Carasso; Paolo Denti; Niklas Schofer; Lenard Conradi

doi:10.1016/j.jaccas.2023.101873

Prevention of LVOT Obstruction by Device-Mediated Laceration of the Anterior Mitral Valve Leaflet During TMVR

Sebastian Ludwig, Daniel Kalbacher, Lara Waldschmidt, Andreas Schaefer, Thomas Modine, Danny Dvir, Shemy Carasso, Paolo Denti, Niklas Schofer, Lenard Conradi

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

Left ventricular outflow tract obstruction represents a life-threatening complication in patients undergoing transcatheter mitral valve replacement. Interventional approaches to prevent left ventricular outflow tract obstruction are complex and require exceptional procedural expertise. We demonstrate feasibility and safety of first-in-human device-mediated mechanical laceration of the anterior mitral valve leaflet prior to transapical transcatheter mitral valve replacement. (Level of Difficulty: Advanced.)

Original language	English
Article number	101873
Journal	JACC: Case Reports
Volume	16
DOIs	https://doi.org/10.1016/j.jaccas.2023.101873
State	Published - 21 Jun 2023
Externally published	Yes

Bibliographical note

Publisher Copyright:
© 2023 The Authors

Keywords

LVOT obstruction
leaflet laceration
transcatheter mitral valve replacement

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10.1016/j.jaccas.2023.101873

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title = "Prevention of LVOT Obstruction by Device-Mediated Laceration of the Anterior Mitral Valve Leaflet During TMVR",

abstract = "Left ventricular outflow tract obstruction represents a life-threatening complication in patients undergoing transcatheter mitral valve replacement. Interventional approaches to prevent left ventricular outflow tract obstruction are complex and require exceptional procedural expertise. We demonstrate feasibility and safety of first-in-human device-mediated mechanical laceration of the anterior mitral valve leaflet prior to transapical transcatheter mitral valve replacement. (Level of Difficulty: Advanced.)",

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author = "Sebastian Ludwig and Daniel Kalbacher and Lara Waldschmidt and Andreas Schaefer and Thomas Modine and Danny Dvir and Shemy Carasso and Paolo Denti and Niklas Schofer and Lenard Conradi",

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AU - Ludwig, Sebastian

AU - Kalbacher, Daniel

AU - Waldschmidt, Lara

AU - Schaefer, Andreas

AU - Modine, Thomas

AU - Dvir, Danny

AU - Carasso, Shemy

AU - Denti, Paolo

AU - Schofer, Niklas

AU - Conradi, Lenard

PY - 2023/6/21

Y1 - 2023/6/21

N2 - Left ventricular outflow tract obstruction represents a life-threatening complication in patients undergoing transcatheter mitral valve replacement. Interventional approaches to prevent left ventricular outflow tract obstruction are complex and require exceptional procedural expertise. We demonstrate feasibility and safety of first-in-human device-mediated mechanical laceration of the anterior mitral valve leaflet prior to transapical transcatheter mitral valve replacement. (Level of Difficulty: Advanced.)

AB - Left ventricular outflow tract obstruction represents a life-threatening complication in patients undergoing transcatheter mitral valve replacement. Interventional approaches to prevent left ventricular outflow tract obstruction are complex and require exceptional procedural expertise. We demonstrate feasibility and safety of first-in-human device-mediated mechanical laceration of the anterior mitral valve leaflet prior to transapical transcatheter mitral valve replacement. (Level of Difficulty: Advanced.)

KW - LVOT obstruction

KW - leaflet laceration

KW - transcatheter mitral valve replacement

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JO - JACC: Case Reports

JF - JACC: Case Reports

M1 - 101873

ER -

Prevention of LVOT Obstruction by Device-Mediated Laceration of the Anterior Mitral Valve Leaflet During TMVR

Abstract

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Keywords

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