Presence of tRNA-dependent pathways correlates with high cysteine content in methanogenic Archaea

Liron Klipcan; Milana Frenkel-Morgenstern; Mark G. Safro

doi:10.1016/j.tig.2007.11.007

Presence of tRNA-dependent pathways correlates with high cysteine content in methanogenic Archaea

Liron Klipcan, Milana Frenkel-Morgenstern, Mark G. Safro

Weizmann Institute of Science

Research output: Contribution to journal › Short survey › peer-review

19 Scopus citations

Abstract

Archeal proteomes can be clustered into two groups based on their cysteine content. One group of proteomes displays a low cysteine content (∼0.7% of the entire proteome), whereas the second group contains twice as many cysteines as the first (∼1.3%). All cysteine-rich organisms belong to the methanogenic Archaea, which generates special cysteine clusters associated with primitive metabolic reactions. Our findings suggest that cysteine plays an important role in early forms of life.

Original language	English
Pages (from-to)	59-63
Number of pages	5
Journal	Trends in Genetics
Volume	24
Issue number	2
DOIs	https://doi.org/10.1016/j.tig.2007.11.007
State	Published - Feb 2008
Externally published	Yes

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Presence of tRNA-dependent pathways correlates with high cysteine content in methanogenic Archaea

Abstract

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