Preparation of formate esters from O-TBDMS/O-TES protected alcohols. A one-step conversion using the Vilsmeier-Haack complex POCl3/DMF

Sylvain Koeller, Jean Paul Lellouche

Research output: Contribution to journalArticlepeer-review

23 Scopus citations

Abstract

O-tert-Butyldimethylsilylated (O-TBDMS) or O-triethylsilylated (O-TES) alcohols were converted in one step to their corresponding formates under Vilsmeier-Haack conditions (POCl3/DMF). The scope and limitations of this novel reaction for interconverting alcohol protecting groups are described.

Original languageEnglish
Pages (from-to)7043-7046
Number of pages4
JournalTetrahedron Letters
Volume40
Issue number38
DOIs
StatePublished - 17 Sep 1999
Externally publishedYes

Keywords

  • Formates
  • Formylation
  • Protecting groups
  • Vilsmeier-Haack reaction

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