Preparation of 2-thiazolines from (1,2)-thioamido-alcohols; DAST as a useful reagent

Pierre Lafargue, Pierre Guenot, Jean Paul Lellouche

Research output: Contribution to journalArticlepeer-review

62 Scopus citations

Abstract

Diethylamidosulfur trifluoride (DAST) is shown to be a valuable reagent for the ready access to 2-thiazolines 4a-f starting from the corresponding (1,2)-thioamido-alcohols 3a-f. This mild intramolecular cyclization is fast (< 1 h) and occurs at a temperature as low as-78 °C.

Original languageEnglish
Pages (from-to)171-172
Number of pages2
JournalSynlett
Volume1995
Issue number2
DOIs
StatePublished - Feb 1995
Externally publishedYes

Bibliographical note

Publisher Copyright:
© 1995 Georg Thieme Verlag, Rudigerstr. 14, 70469 Stuttgart, Germany. All rights reserved.

Keywords

  • 2-Thiazolines
  • DAST

Fingerprint

Dive into the research topics of 'Preparation of 2-thiazolines from (1,2)-thioamido-alcohols; DAST as a useful reagent'. Together they form a unique fingerprint.

Cite this