Predictors of cesarean delivery after prelabor rupture of membranes at term

David Peleg, Mary E. Hannah, Ellen D. Hodnett, Gary A. Foster, Andrew R. Willan, Dan Farine, M. E. Hannah, A. Ohlsson, D. Farine, S. A. Heivson, E. D. Hodnett, T. L. Myhr

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

Objective: To identity the significant predictors of cesarean delivery after prelabor rupture of membranes (PROM) at term. Methods: In a multicenter study involving 72 institutions in six countries, 5041 women were randomized to induction of labor with oxytocin or prostaglandins or to expectant management. We did univariate and multivariate logistic regression analyses to determine the statistically significant independent predictors of cesarean delivery (P < .05). Results: The following variables were found to be significantly associated with cesarean delivery: delivery in Israel, versus Canada (odds ratio [OR] 0.34); delivery in Australia, versus Canada (OR 1.93); nulliparity (OR 2.81); labor lasting more than 12 hours, versus less than 6 hours (OR 2.78); labor lasting 6-12 hours, versus less than 6 hours (OR 1.66); previous cesarean delivery (OR 2.75); epidural anesthesia (OR 2.66); clinical chorioamnionitis (OR 2.42); internal fetal heart rate monitoring (OR 2.19); birth weight of at least 4000 g (OR 2.07); use of oxytocin (OR 1.97); maternal age of at least 35 years (OR 1.44); latent period of at least 12 hours (OR 1.41); and meconium staining (OR 1.41). Conclusion: Strong predictors of cesarean delivery after PROM at term were country of birth, nulliparity, long labor, previous cesarean delivery, and epidural anesthesia.

Original languageEnglish
Pages (from-to)1031-1035
Number of pages5
JournalObstetrics and Gynecology
Volume93
Issue number6
DOIs
StatePublished - Jun 1999
Externally publishedYes

Bibliographical note

Funding Information:
Supported by Medical Research Council of Canada grant no. MA-11392.

Funding Information:
This study was a retrospective analysis of data, so there might be other fetal and maternal factors associated with cesarean delivery after PROM concerning which we had no or inadequate information. We had no information on environmental factors other than country of birth. Future prospective research should involve evaluation of changes in environment, while controlling for fetal and maternal factors. The ongoing Nursing SCIL Trial, funded by the National Institutes of Health, coordinated in Toronto by EDH, is an example of such an evaluation. The Nursing SCIL Trial is a multicenter, randomized controlled trial evaluating the effect of continuous, supportive care in labor by nurses in institutions in the United States and Canada.

Funding

Supported by Medical Research Council of Canada grant no. MA-11392. This study was a retrospective analysis of data, so there might be other fetal and maternal factors associated with cesarean delivery after PROM concerning which we had no or inadequate information. We had no information on environmental factors other than country of birth. Future prospective research should involve evaluation of changes in environment, while controlling for fetal and maternal factors. The ongoing Nursing SCIL Trial, funded by the National Institutes of Health, coordinated in Toronto by EDH, is an example of such an evaluation. The Nursing SCIL Trial is a multicenter, randomized controlled trial evaluating the effect of continuous, supportive care in labor by nurses in institutions in the United States and Canada.

FundersFunder number
National Institutes of Health
Medical Research Council CanadaMA-11392

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