Predictive factors for focal disease in human brucellosis, an observational cohort study

Halima Dabaja-Younis; Menas Atarieh; Michal Paul; Elias Nasrallah; Yuval Geffen; Imad Kassis; Nesrin Ghanem-Zoubi

doi:10.1007/s10096-022-04541-1

Predictive factors for focal disease in human brucellosis, an observational cohort study

Halima Dabaja-Younis
, Menas Atarieh
, Michal Paul
, Elias Nasrallah
, Yuval Geffen
, Imad Kassis
, Nesrin Ghanem-Zoubi

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

This retrospective cohort study aimed to identify predictors for focal disease in human brucellosis. The study included patients with brucellosis diagnosed between January 2000 and December 2021. Overall, 247 patients were identified. Focal disease was diagnosed in 64 (25.9%) patients. The most common focal infection was bone and joint in 56 patients (23.4%). Disease duration > 14 days was significantly associated with focal illness [OR = 2.2 (1.08–4.47), p = 0.030], although febrile illness was inversely associated with focal illness this did not reach statistical significance [OR = 0.46 (0.21–1.00), p = 0.050]. Focal brucellosis should be suspected in patients with prolonged illness.

Original language	English
Pages (from-to)	221-226
Number of pages	6
Journal	European Journal of Clinical Microbiology and Infectious Diseases
Volume	42
Issue number	2
DOIs	https://doi.org/10.1007/s10096-022-04541-1
State	Published - Feb 2023
Externally published	Yes

Bibliographical note

Publisher Copyright:
© 2022, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Brucellosis
Complications
Focal
Unfavorable

Access to Document

10.1007/s10096-022-04541-1

Cite this

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title = "Predictive factors for focal disease in human brucellosis, an observational cohort study",

abstract = "This retrospective cohort study aimed to identify predictors for focal disease in human brucellosis. The study included patients with brucellosis diagnosed between January 2000 and December 2021. Overall, 247 patients were identified. Focal disease was diagnosed in 64 (25.9\%) patients. The most common focal infection was bone and joint in 56 patients (23.4\%). Disease duration > 14 days was significantly associated with focal illness [OR = 2.2 (1.08–4.47), p = 0.030], although febrile illness was inversely associated with focal illness this did not reach statistical significance [OR = 0.46 (0.21–1.00), p = 0.050]. Focal brucellosis should be suspected in patients with prolonged illness.",

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AU - Geffen, Yuval

AU - Kassis, Imad

AU - Ghanem-Zoubi, Nesrin

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Predictive factors for focal disease in human brucellosis, an observational cohort study

Abstract

Bibliographical note

UN SDGs

Keywords

Access to Document

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