Prediction of protein interaction sites

Yanay Ofran

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

10 Scopus citations

Abstract

Proteins recognize and bind to each other through interaction sites. Hence, understanding the mechanisms that underlie protein–protein interaction requires the elucidation of the characteristics of interaction sites. Analysis of interaction sites have revealed some of their commonalities and suggested that it may be possible to identify these sites a priori. Prediction methods that identify protein interaction sites from the structure or even the sequence of a protein will enhance the study of protein–protein interaction, and may break new grounds in protein design and even in the development of drugs.

Original languageEnglish
Title of host publicationComputational Protein-Protein Interactions
PublisherCRC Press
Pages167-184
Number of pages18
ISBN (Electronic)9781420070071
ISBN (Print)9781420070057
DOIs
StatePublished - 1 Jan 2009

Bibliographical note

Publisher Copyright:
© 2009 by Taylor and Francis Group, LLC.

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